The raid in Kandahar province on Thursday targeted a bomb-maker responsible for roadside bomb attacks that killed NATO soldiers, a coalition statement said.
Militants barricaded themselves inside a home during the raid and opened fire on the coalition forces. After giving time to allow women and children to leave, the coalition forces fired on the militants with guns and grenades, it said.
One woman who remained in the building was wounded in the leg. She was evacuated to a coalition medical facility, it said.
Coalition forces found dozens of land mines, grenades, AK-47s and bomb-making materials in the home, the coalition said.
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